Multiscale analysis of stochastic spatial chemical reaction networks (13rit182)


(University of Freiburg)

Lea Popovic (Concordia University)


The Banff International Research Station will host the "Multiscale analysis of stochastic spatial chemical reaction networks" workshop from to .

Recent advances in measurement technology have enabled scientists to observe molecular dynamics in single cells and to study the cell-to-cell variability. Understanding how intracellular mechanisms are affected by this intrinsic noise is an important challenge for systems biology, and determining what role this noise plays in creating phenotypic heterogeneity has many practical consequences. In the context of cellular systems of biochemical reactions, the problem of determining the stochastic effects due to cell heterogeneity is experimentally challenging. The development of computational approaches and analytical results to understand these dynamic processes is essential for the elucidation of cellular mechanisms. A rigorous stochastic approach to this problem poses many interesting and challenging mathematical questions explored in our proposed activity.

The Banff International Research Station for Mathematical Innovation and Discovery (BIRS) is a collaborative Canada-US-Mexico venture that provides an environment for creative interaction as well as the exchange of ideas, knowledge, and methods within the Mathematical Sciences, with related disciplines and with industry. The research station is located at The Banff Centre in Alberta and is supported by Canada's Natural Science and Engineering Research Council (NSERC), the U.S. National Science Foundation (NSF), Alberta's Advanced Education and Technology, and Mexico's Consejo Nacional de Ciencia y Tecnología (CONACYT).